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Release Notes

Last Updated: December 2024

Release Date: December 2024

These release notes describe the key changes to Illumina Preset Protocols (IPP) v2.10.

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Compatibility

Refer to Compatibility under Instruments & Integrations.

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New Features & Updates

  • Added a new MiSeq i100 Series Sequencing v1.0 protocol that supports the new MiSeq i100 Series Integration Package v1.0.

  • Added a new MiSeq i100 Series On-Prem Sequencing v1.0 protocol that supports the new MiSeq i100 Series On-Prem Integration Package v1.0.

  • Added a new NovaSeq X Series On-Prem Sequencing v1.0 protocol that supports the new NovaSeq X Series On-Prem Integration Package v1.0.

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Conflicts are expected when upgrading from IPP v2.9 to IPP v2.10 due to new instruments being supported, updates to the configuration settings of BP Aliquot Volume (ul) global field, and bug fixes for NovaSeq X Series Sequencing v1.1 protocol. Refer to for details.

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Known Issues

Importing workflows from IPP on Clarity v6.2 and v6.3 requires longer time (~8 times longer) compared to earlier versions (Clarity v6.1 and below). This issue is fixed in Clarity v6.3.1.

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Additional References

Refer to these additional release notes for new features, updates and defects fixed for instrument integration protocols:

The updated NovaSeq X Series Sequencing v1.2 protocol supports NovaSeq X Series Integration Package v1.3.
  • The updated NextSeq 500/550 Sequencing v1.3 protocol supports NextSeq 500/550 Integration Package v2.5.

  • The updated Library Prep Validation v2.3.5 protocol now displays an expanded sample table under the Record Details milestone by default.

  • IPP Integration v2.10 Manual Upgrade
    MiSeq i100 Series On-Prem Integration v1.0.0 Release Notes
    MiSeq i100 Series Integration v1.0.0 Release Notes
    NextSeq 500/550 Integration v2.5.0 Release Notes
    NovaSeq X Series On-Prem Integration v1.0.0 Release Notes
    NovaSeq X Series Integration v1.3.0 Release Notes