# Release Notes

Release Date: November 2025

These release notes describe the key changes to Illumina Preset Protocols (IPP) v2.11.

## Compatibility

Refer to [Compatibility](https://help.connected.illumina.com/clarity-lims/instruments-and-integrations/compatibility#illumina-preset-protocol) under Instruments & Integrations.

## New Features & Updates

* The updated MiSeq i100 Series Sequencing v2.0 protocol supports MiSeq i100 Series Integration Package v1.1.0 and MiSeq i100 Series On-Prem Integration Package v1.1.0.

{% hint style="danger" %}
Conflicts may occur when upgrading from IPP v2.10 to IPP v2.11 due to new sequencing workflow for MiSeq i100 Series. Refer to [IPP Integration v2.11 Manual Upgrade](https://help.connected.illumina.com/clarity-lims/illumina-preset-protocols/ipp-v2.11/ipp-v2.11.0-manual-upgrade) for details.
{% endhint %}

* Added new parameters (`--removeOnPremConfig` and `--removeUPA`) to Illumina Preset Protocol Installer. Refer to [Illumina Preset Protocols v2.11 Installation and User Configuration](https://help.connected.illumina.com/clarity-lims/illumina-preset-protocols/ipp-v2.11.0-installation-and-user-configuration#installer-parameters-and-operations) for details.

## Known Issues

Importing workflows from IPP on Clarity v6.2 and v6.3 requires longer time (\~8 times longer) compared to earlier versions (Clarity v6.1 and below). This issue is fixed in Clarity v6.3.1.

## Additional References

Refer to these additional release notes for new features, updates and defects fixed for instrument integration protocols:

* [MiSeq i100 Series On-Prem Integration v1.1.0 Release Notes](https://help.connected.illumina.com/clarity-lims/instruments-and-integrations/miseq-i100/miseqi100-onprem/miseqi100-onprem-v1.1.0/miseqi100-onprem-v1.1.0-release-notes)
* [MiSeq i100 Series Integration v1.1.0 Release Notes](https://help.connected.illumina.com/clarity-lims/instruments-and-integrations/miseq-i100/miseqi100/miseqi100-v1.1.0/miseqi100-v1.1.0-release-notes)