# Release Notes

Last Updated: December 2024

Release Date: December 2024

These release notes describe the key changes to software components for the Clarity LIMS MiSeq i100 Series Integration Package v1.0.0.

## **Compatibility**

Refer to [Compatibility](/clarity-lims/instruments-and-integrations/compatibility.md#miseq-i100-series) under Instruments & Integrations.

## **New Features**

* Provides integration between the MiSeq i100 Series instrument and Illumina cloud-hosted Clarity LIMS.
* Supports creation of planned run with secondary analysis configuration and generation of v2 sample sheet for Cloud and Hybrid run modes via Illumina Connected Analytics (ICA).
* Supports automated tracking of the sequencing run and parsing of run metrics to Illumina cloud-hosted Clarity LIMS.
* Supports automated tracking of analysis for analysis status and demultiplexing results. The analysis is either performed by ICA in Cloud run mode or by DRAGEN on-premise in Hybrid run mode.
* New MiSeq i100 Series Sequencing v1.0 workflow available from Illumina Preset Protocol v2.10.

## **Known Limitations**

* The Assign Analysis Configuration Template step does not support pooled libraries.
* For local analysis (Hybrid run mode), custom library prep and index adapter kits selected in the ACT must also be installed or created in the Illumina Run Manager.


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