# Test Definitions

Test Definitions allow you to specify default parameters that apply to cases when they are ingested. Make sure you have test components created, then create a test definition as follows.

1. On the top toolbar, select **Configuration**.
2. Select the **Test Definitions** tab.
3. Select **New**.
4. In the right-hand pane, enter a test name in the Test Name field.
5. Choose a human reference genome.
6. \[Optional] Select one or more custom annotations (must be compatible for the selected human reference genome).
7. Choose one or more variant filters. These filters display in the [Variants Tab](https://help.connected.illumina.com/connected-insights/interpret-and-report/inter-variant-grid) as locked filters.
8. Choose a [variant flag group](https://help.connected.illumina.com/connected-insights/configure/configuration/c-variant-flag-groups).
9. Choose a [report template](https://help.connected.illumina.com/connected-insights/configure/configuration/reports-report-templates).
10. \[Optional] Enter version comments as applicable.
11. \[Optional] Select the **Turn on Report Automation** toggle to enable or disable the automated addition of assertions to reports using this test definition. For more information, refer to [Report Automation](https://help.connected.illumina.com/connected-insights/configure/configuration/c-automation).
12. \[Optional] Enter a test methodology to be included on the PDF report.
13. Select **Save**. The new test definition appears on the left-hand accordion menu. Select a test definition to preview and access the following actions:
    * Select **Edit** to edit a test definition.
    * Select **Copy as New Test** to copy the definition as a template for a new test definition.
    * Select **Archive** to hide the test definition from the PDF report.

## Default Tests

Connected Insights provides the following default tests to assist in preliminary test implementation:

| GRCh37 Demo     | GRCh37 test that applies filters for oncogenic, likely oncogenic, 1A, 1B, and 2C DNA and RNA variants. |
| --------------- | ------------------------------------------------------------------------------------------------------ |
| GRCh38 Demo     | GRCh38 test that applies filters for oncogenic, likely oncogenic, 1A, 1B, and 2C DNA and RNA variants. |
| GRCh38 AML Demo | GRCh38 test that applies filters for AML-related variants based on WHO 2022 and ELN 2022 guidelines.   |