# Data Upload

This section describes how to upload data with Connected Insights and includes setup instructions. Connected Insights requires the following data types:

* **Secondary analysis output data** — Connected Insights is compatible with a broad range of analysis pipeline outputs. To configure the input file format, select a compatible pipeline (for example, DRAGEN TruSight Oncology 500 v2.5.2) or configure a custom pipeline.
* **Case, subject, and sample data** — Connected Insights will read case, subject, and sample data passed along with the analysis pipeline outputs when available from the following files:\
  \&#xNAN;*Samplesheet.csv* - Will read Sample\_ID, Tumor\_Type, Pair\_ID, Sample\_Type, and Sex.\
  \&#xNAN;*Fastq-list.csv* - Will read RGSM to determine Sample Id.\
  \&#xNAN;*Replay.json* - Will determine Sample Id for tumor (and normal) sample(s).\
  For more information on custom case data such as to upload additional case metadata, refer to [Custom Case Data Upload](https://help.connected.illumina.com/connected-insights/configure/configuration/du-introduction/du-custom-case-dataupload)

Connected Insights - Cloud allows data upload from the following sources:

* **User storage** — Data ingestion is managed by the Data Uploader tool that supports uploading variant call format (VCF) files and other analysis output files. For more information, refer to [Data Upload from User Storage (Connected Insights - Local Storage)](https://help.connected.illumina.com/connected-insights/configure/configuration/du-introduction/du-user-storage).
* **From computer via browser** - Data ingestion supports upload of a single tumor-only VCF through the browser. For more information on manual upload from computer, refer to [Data Upload from Computer](https://github.com/illumina-swi/ici-docs/blob/main/docs/configure/configuration/du-introduction/du-browser-upload.md).
* **Cloud storage on ICA and BSSH** — Data ingestion can be configured through the Data Upload page or API. For more information on using the Data Upload tab or API, refer to [Data Upload from ICA (Connected Insights - Cloud)](https://help.connected.illumina.com/connected-insights/configure/configuration/du-introduction/du-ica).

Before uploading, create the following items:

* Custom case data (if applicable)
* Test components
* Test definitions (for more information on creating test components and definitions, refer to [Test Definition Setup](https://help.connected.illumina.com/connected-insights/configure/configuration/c-test-definition-setup))