The following Types of Analysis are currently supported by DRAGEN Array:
DRAGEN Array – Genotyping
DRAGEN Array – PGx – CNV calling
DRAGEN Array – PGx – Star allele annotation
DRAGEN Array - Methylation QC
Summary
Provides genotyping results for any human Infinium genotyping array.
Variant types detected
SNV
Indel
Sample minimum
1 sample
Arrays supported
Related Local Commands
Genotype Call
Genotype GTC-to-VCF
Related Cloud Specifics
Select Type of Analysis DRAGEN Array - Genotyping from the dropdown. Max 1152 samples are supported.
Inputs
Outputs
Per sample:
Per analysis batch:
Cost
Summary
Provides CNV calling on 6 target PGx genes across 9 target regions, plus genotyping outputs.
Variant types detected
SNV
Indel
CNV
Sample minimum
Minimum of 24 samples with 22 passing QC defined as Log R Dev < 0.2. 96 samples are recommended for best results.
Arrays supported
Related Local Commands
Genotype Call
Genotype GTC-to-VCF [optional]
Copy-number Call
Related Cloud Specifics
Select Type of Analysis DRAGEN Array - PGx – CNV calling from the dropdown. Max 384 samples are supported.
Inputs
Outputs
Per sample:
Per analysis batch:
Cost
Summary
Provides PGx annotation on over 50 genes, plus PGx CNV and genotyping outputs
Variant types detected
SNV
Indel
CNV
Star allele diplotype
Sample minimum
Minimum of 24 samples with 22 passing QC defined as Log R Dev < 0.2. 96 samples are recommended for best results.
Arrays supported
Related Local Commands
Genotype call
Genotype GTC-to-VCF [optional]
Copy-number call
Star-allele call
Star-allele annotate
Related Cloud Specifics
Select Type of Analysis DRAGEN Array - PGx – Star Allele Annotation from the dropdown. Max 384 samples are supported.
Inputs
Outputs
Per sample:
Per analysis batch:
Cost
Local: Per sample analysis.
Summary
Provides methylation QC for Infinium methylation arrays.
Variant types detected
N/A
Sample minimum
1 sample
Arrays supported
Recommended thresholds and all built-in control probes are available for Methylation Screening Array (MSA) and MethylationEPIC (v1 & v2) originating from iScan. In non-human and custom arrays, availability of built-in QC probes may vary, and failure thresholds must be defined by the user.
Related Local Commands
Not available on DRAGEN Array Local.
Related Cloud Specifics
Inputs
Outputs
Cost
Any human Infinium genotyping array including custom and semi-custom to create a SNV VCF output. Illumina provides required to map to the reference genome for human, genome build 37 and 38. DRAGEN Array Cloud offers additional output formats including Locus Summary and Final Report which are applicable for Infinium arrays for human and non-human species.
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• [may be pre-setup on cloud]
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Local: No cost download from .
Cloud: to analyze and store data as needed.
Global Diversity Array with Enhanced PGx ()
See for further detail.
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• [may be pre-setup on cloud]
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Local: No cost download from .
Cloud: to analyze and store data as needed.
Global Diversity Array with Enhanced PGx ()
See for further detail.
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• [may be pre-setup on cloud]
• [may be pre-setup on cloud]
• [pre-setup on cloud]
• [pre-setup on cloud]
• [pre-setup on cloud]
• [optional on cloud and local]
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• [optional on local]
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• [optional on local]
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Cloud: Per sample analysis. to store data as needed.
Visit the to learn more.
Select Type of Analysis DRAGEN Array – Methylation – QC from the dropdown. Adjust customizable thresholds as desired. Further detail can be found in Additional information for . A maximum of 1152 samples are supported, when sample sheet is used.
• [from iScan instrument] • [may be pre-setup on cloud] • [optional on cloud]
Per sample: • • Per analysis batch: • • • • •
Cloud: to analyze and store data as needed.