# Frequently Asked Questions

1. **Is DRAGEN Array analysis a local (on-premises) or cloud solution?**\
   DRAGEN Array analysis is available locally (on-premises) and cloud.\\

   DRAGEN Array Local Analysis utilizes a command-line interface for power users to have granular control and flexibility to support large scale microarray genomic studies. Deployed on Windows or Linux operating systems, the local package is CPU-based and does not require a specialized server or hardware.\\

   DRAGEN Array Cloud Analysis utilizes the user-friendly, graphical interface of BaseSpace Sequence Hub to simplify analysis setup and kickoff.\\
2. **Which Infinium arrays is DRAGEN Array compatible with?**\
   **Genotyping**: DRAGEN Array can produce GTC files for any Infinium genotyping array. For customers interested in obtaining a genotyping VCF file, any human genotyping array is supported. Conversion to VCF requires a FASTA file input. Illumina provides FASTA files for human genome build 37 and 38 on the support site.\\

   **Pharmacogenomics**: Global Diversity Array with Enhanced PGx is supported for PGx CNV calling and star allele calling. Manifest version E and later should be used.\\
3. **How many samples are needed per analysis?**\
   **Genotyping:** As few as one sample can be used for genotyping. Multiple analysis batches can be kicked off and run in parallel.\\

   **Pharmacogenomics:** A minimum of 24 samples is required for PGx CNV calling with 22 passing QC. Passing QC is defined as Log R Dev < 0.2. 96 samples are recommended for the most accurate CNV results. Multiple analysis batches can be kicked off and run in parallel.\\
4. **Which PGx CNVs and star alleles are available?**\
   Please refer to the DRAGEN Array [release notes](https://help.connected.illumina.com/dragen-array/dragen-array-v1.0/reference/release-notes).\\
5. **Where can I find demo data?**\
   Demo data is available in BaseSpace under the “Demo Data” section. All array data starts with “iScan:” and includes the name of the type of analysis. Supported types of analysis can be found in the [Applications](https://help.connected.illumina.com/dragen-array/dragen-array-v1.0/overview/our-features) section.\\
