# Advanced Topics ## Overview The pipeline supports advanced use cases: * Selected custom parameters may be configured using a configuration file, and associated custom pipeline resource files. * The pipeline supports automatic data streaming from instruments and automatic launch of analysis in ICA, followed by tertiary interpretation in ICI. * The pipeline supports mix flow cells where different assays are sequenced in the same flow cell. --- # Agent Instructions: Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter: ``` GET https://help.connected.illumina.com/dragen-clinical-research-apps/readme/dragen-heme-wgs-to-pipeline/setup/advanced.md?ask= ``` The question should be specific, self-contained, and written in natural language. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.