Reference Database

DRAGEN miRNA offers users the option to select from two reference databases. This section outlines the process of constructing these databases.

Reference v21

Mature miRNA and miRNA hairpin libraries were obtained from miRBase.org using version v21. Human (Homo sapiens), mouse (Mus musculus), rat (Rattus norvegicus), fruitfly (Drosophila melanogaster), nematode (Caenorhabditis elegans) and zebrafish (Danio rerio) mRNA and other noncoding RNA libraries were obtained from Ensembl (www.ensembl.org/), unless otherwise denoted. Human tRNAs were obtained from the Genomic tRNA Database. Human snoRNA was obtained from the snoRNABase (www-snorna.biotoul.fr/).

Reference v22

The libraries used when selecting reference v22 are available here SourceForge. Mature miRNA and miRNA hairpin libraries were obtained from miRBase.org using version v22.

Available Species

List of species supported in the software (compatible with both v21 and v22):

• Human (Homo sapiens)

• Mouse (Mus musculus)

• Rat (Rattus norvegicus)

• Fruitfly (Drosophila melanogaster)

• Nematode (Caenorhabditis elegans)

• Zebrafish (Danio rerio)