# Documentation Revision History

<table><thead><tr><th width="146.22216796875">Date</th><th>Changes Made</th></tr></thead><tbody><tr><td>March 2025</td><td>Initial Release</td></tr><tr><td>May 2025</td><td><ul><li>Multiomic Walkthrough Updated</li><li>ADAT Compatibility with Excel Added</li></ul></td></tr><tr><td>June 2025</td><td><p>Release with DRAGEN Protein Quantification v2.1.0</p><ul><li><p>Changes to ADAT Content</p><ul><li>Header: Addition of Median, Q75, Q90 Intra-Plate and Inter-Plate CVs</li><li>Header: Removal of PlateRefCorr_PassFlag</li><li>SOMAmer metadata clean up</li><li>SOMAmer metadata: Removal of PassFlags for Calibration and QC: not used for analysis</li><li>Sample metadata: EmpHybTemp_PassFlag added</li><li>Sample metadata: RefCorr_PassFlag removed</li><li>Sample metadata: MedNormInt_PassFlags for serum, plasma and QC samples, and MedNormExt_PassFlags from blank and calibrator samples removed</li></ul></li><li>Updated hybridization normalization to only use calibrator and QC samples</li><li>DRAGEN Application Manager support</li></ul></td></tr><tr><td>September 2025</td><td><ul><li>Updated 6k and 9.5k SeqID lists in multiomics walkthrough</li><li>Updated SW version to v2.2.2</li></ul></td></tr><tr><td>November 2025</td><td><ul><li>Added Known Limitations page</li></ul></td></tr><tr><td>February 2026</td><td><p>Release with DRAGEN Protein Quantification v2.3.0</p><ul><li>Changes to ADAT output directory structure and filenames</li><li>Introduction of PLATE_FAIL for sample-level RowCheck_Flag  </li></ul></td></tr></tbody></table>


---

# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://help.connected.illumina.com/dragen-protein-quantification/references/documentation-revision-history.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.