Workflow Overview

The DRAGEN for IDT Custom Panels workflow is a verified workflow that supports the flexibility needed for custom panels while delivering reproducible results with minimal parameter tuning. The workflow has three entry points to meet customers where they are.

The DRAGEN for IDT Custom Panels workflow enables a verified workflow that complies with the flexibility needed for custom panels but delivers reproducible results with minimal parameter tunning required.

Two-Stage Analysis

Regardless of which entry point you choose, the analysis consists of two stages that must be run in order:

1. Stage 1: Generate a systematic noise baseline file. See Stage 1: Generate Systematic Noise File.

1. Stage 2: DRAGEN somatic for IDT custom panels variant calling. See Stage 2: Run Variant Calling.

NOTE. The output VCF can be ingested into Illumina Connected Insights for tertiary analysis interpretation.

Next Step

Use Choose Your Entry Point to decide whether to launch from Run Planner, the BSSH application, or the ICA pipeline.