> For the complete documentation index, see [llms.txt](https://help.connected.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.connected.illumina.com/dragen-stratamap/dragen-spatial-transcriptome/getting-started/dragen-app-manager-local.md).

# DRAGEN App Manager (Local)

The DRAGEN Spatial Transcriptome Application enables on-premise analysis of spatial transcriptomics data from Illumina sequencing instruments. This application processes sequencing data (BCL files) along with map files and microscopy images to generate spatially resolved gene expression profiles.

#### Key Features

* High-performance analysis powered by DRAGEN hardware acceleration
* Flexible input options supporting both image-based and imageless workflows
* Comprehensive outputs including raw counts, grid-binned, and cell-binned expression matrices
* Automated quality control with detailed reports

{% hint style="info" %}
While the Local App enables fully local operation, it is important to understand that it is much more limited in capability, scalability, and performance compared to the cloud-based version of the application. Customers who require larger-scale analysis, faster runtimes, or advanced features may benefit from using the cloud version instead.
{% endhint %}


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