# Block List

The block list represents high noise regions in the panel where false positive variant calls are likely produced. As a result, all positions in the gVCF are marked as Filter=excluded\_regions to indicate variant call results are not reliable in such regions.

The block list includes the following genes:

* HLA A
* HLA B
* HLA C
* KMT2B
* KMT2C
* KMT2D
* chrY
* Any position with VAF 1% occurrence in six or more of the 60 baseline samples.