You can run DRAGEN analysis on Microsoft Azure. For information on using DRAGEN, see the DRAGEN User Guide Section. For information on using Azure, see the Azure documentation available on the Microsoft site.
A QuickStart for DRAGEN on Azure is avaialble here DRAGEN on Azure QuickStart
If you are using an Azure Batch account, see DRAGEN on Azure Batch for more information.
To use the DRAGEN Software for genomic data analysis on Azure, the following are required:
DRAGEN Multi-Cloud license. For more information, contact Illumina Technical Support.
Azure cloud subscription.
Quota for NP-series virtual machines (VM).
Azure command-line interface (CLI). For instructions on installing the Azure CLI, see the Azure documentation available on the Microsoft site.
Genomic data uploaded to your Azure Blob storage account.
DRAGEN on Azure is available in the following regions with field programmable gate array (FPGA)-enabled, standard NP-series virtual machines.
West US 2
East US
South Central US
West Europe (Amsterdam)
Southeast Asia (Singapore)
DRAGEN requires FPGA hardware. You must request access to the FPGA-enabled, NP-series VMs.
The vCPU requirements for NP-series SKUs are in increments of 10. When requesting an updated quota, DRAGEN recommends requesting vCPUs in batches of 10. The instructions for running DRAGEN on Azure require a minimum increase of 10 vCPU quotas for NP-series machines.
To make sure you have quota for NP-series VMs or to increase a quota, navigate to your Microsoft Azure portal, and then do as follows.
Select Subscriptions, then choose your subscription.
Under Settings, select Usage + quotas.
Enter NP into the search bar to filter for the NP-series. The quota list displays Standard NPS Family vCPUs.
If you do not see any results, select Request Increase. For more information on requesting quota for NP-series VMs, see the Azure documentation available on the Microsoft site.
Use the following information to run the DRAGEN virtual machine (VM) on Microsoft Azure. For information on using Azure, see the Azure documentation available on the Microsoft site.
Navigate to the Microsoft Azure portal, and then sign in.
Select Marketplace.
Select View Private Offers, and then select DRAGEN on Azure.
Select Create. Starting from a preset configuration option is not recommended for DRAGEN.
Select a subscription and resource group from the drop-down menus, or select Create New.
Enter a name for the virtual machine.
Select a region that is compatible with the NP-series. See the Azure documentation available on the Microsoft site for more information.
Select DRAGEN and the current version as the image.
Select a storage size from the Size drop-down list. Only NP10 and NP20 sizes are compatible.
Configure any additional VM settings. For your disk type, DRAGEN recommends using Premium SSD for optimal performance. For information, see the Azure documentation available on the Microsoft site.
When finished, select Review + Create
To launch the VM, select Create.
After deployment completes, select Go to Resource. After your VM deploys, you can connect to the DRAGEN VM via the Azure Cloud Shell or another client of your choice. For more information on using a VM, see the Azure documentation available on the Microsoft site.