Instructions to install DRAGEN TSO 500 Analysis Application on NovaSeq 6000Dx (RUO mode).
Illumina distributes Illumina DRAGEN TruSight Oncology 500 (HRD) Analysis Application on NovaSeq 6000Dx globally (except Japan) for TSO 500 assay with and without HRD add-on kit. In Japan, Illumina distributes Illumina DRAGEN TruSight Oncology 500 Analysis Application on NovaSeq 6000Dx for TSO 500 assay without HRD.
A NovaSeq 6000Dx sequencing instrument with paired DRAGEN server v4.
Illumina Run Manager installed by Illumina support personnel.
HRD license installed on the DRAGEN server v4 (not required for customers in Japan)
The user installing the app must have admin privileges on Illumina Run Manager.
Contact Illumina Customer Care at customercare@illumina.com to obtain installation package for Illumina DRAGEN TruSight Oncology 500 (HRD) Analysis Application on NovaSeq 6000Dx
If you are a customer in Japan, request Illumina DRAGEN TruSight Oncology 500 Analysis Application on NovaSeq 6000Dx
Download the installation package provided in the email by Illumina Customer Care. The link will expire after 7 days.
It is recommended to use a command line tool like wget or curl to download the file rather than pasting the link into the web browser bar. For example:
curl -o {filename} "{link}"
wget -O {filename} '{link}'
Where the file name is the name of either DRAGEN TSO 500 Analysis Application file or DRAGEN ires file, and the link is provided by Illumina Customer Care.
The installation package contains the following:
DRAGEN TSO 500 Analysis Application: DRAGEN_TSO500HRD_v2.6.0-2v12.iapp
If you are a customer in Japan, you will be provided DRAGEN_TSO500S_v2.6.0-2v12.iapp
DRAGEN ires: drageninstaller_3.10.17-8.el8.x86_64_prod.ires
MD5sum for the installation package contents are as follows:
drageninstaller_3.10.17-8.el8.x86_64_prod.ires
12df06502776d8b673c73fb714dc466a
DRAGEN_TSO500HRD_v2.6.0-2v12.iapp
dc4fe5fe2fc3eca57969e978886dcedf
DRAGEN_TSO500S_v2.6.0-2v12.iapp
74c11da34aeac8fba616bc6763cededa
Install the DRAGEN version using the ires:
Log into Illumina Run Manager as a user with admin credentials
Navigate to the top left menu to "DRAGEN" in the drop down
Select "Add DRAGEN Installer" and upload the DRAGEN ires file
The installation is complete once the DRAGEN version 3.10.17 is in the install version(s) list.
\