# Case quality section The Case quality section summarizes the data quality of the case and highlights the results of validation checks: * Chromosome validation Confirms that each chromosome with at least 100 SNVs in defined enrichment kit or coding regions includes at least one high-quality variant * gnomAD validation Verifies that each chromosome with at least 100 SNVs in defined enrichment kit or coding regions includes at least one variant annotated with gnomAD * ClinVar validation Ensures that each chromosome with at least 100 SNV variants in defined enrichment kit or coding regions includes at least one variant annotated with ClinVar * AI Shortlist validation Checks that at least one variant is tagged by the AI Shortlist. * This validation is not applicable if the gene list contains fewer than 50 genes * If your workgroup uses a higher threshold, it is reflected in the Gene list threshold field * mtDNA reference validation\ Confirms that the rCRS reference is used for mitochondrial DNA --- # Agent Instructions: Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter: ``` GET https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/reviewing_a_case/lab_tab/case-quality-section.md?ask= ``` The question should be specific, self-contained, and written in natural language. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.