Modifying database settings

Users with appropriate permissions can tune database settings within their organization.

1

Click Edit next to the database you want to update.

2

Modify database settings as needed:

• Active: Turn on to apply annotations from this database to variants in new and reanalyzed cases.

• AI Shortlist: Turn on to include allele frequencies from this database when prioritizing variants. When enabled, variants with an allele frequency greater than 10% are excluded from the shortlist.

3

Click Save to apply the changes.

Editing an organization database is automatically recorded in the organization’s audit log for transparency and traceability.