> For the complete documentation index, see [llms.txt](https://help.connected.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.connected.illumina.com/emedgene/emedgene-curate-manual/curate_overview/genome_assemblies_supported_by_curate.md). # Genome assemblies supported by Curate *Curate* supports both GRCh37/hg19 and GRCh38/hg38 genome assemblies. Each time the variant is added to the knowledge base, its genomic coordinates can be converted on-the-fly from one assembly to another. To change the genome assembly, click on the *Human reference* icon and select the genome assembly you wish to use. ![](/files/gm2qaxADMwUkPjYEv8eL) --- # Agent Instructions This documentation is published with GitBook. GitBook is the documentation platform designed so that both humans and AI agents can read, navigate, and reason over technical content effectively. Learn more at gitbook.com. ## Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter, and the optional `goal` query parameter: ``` GET https://help.connected.illumina.com/emedgene/emedgene-curate-manual/curate_overview/genome_assemblies_supported_by_curate.md?ask=&goal= ``` `ask` is the immediate question: it should be specific, self-contained, and written in natural language. `goal` is optional and describes the broader end goal you are ultimately trying to accomplish on behalf of the user. GitBook uses it to tailor the answer towards what is most useful for that goal. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.