> For the complete documentation index, see [llms.txt](https://help.connected.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.connected.illumina.com/emedgene/release-notes/knowledgebase_updates/2024/variant_databases_-february_5th_2024.md).

# Variant Databases (April 9th 2024)

<img src="https://img.freepik.com/premium-vector/red-triangle-caution-warning-sign-danger-symbol-flat-vector-risk-sign_32996-2570.jpg" alt="" data-size="line"> Following the recent updates in ClinVar, some discordance could be observed between aggregate classification and submissions. Indeed, some of the submissions are "flagged" and thus do not contribute to the aggregate classification or review status for the variant. This could be particularly significant when applying ACMG classification rules while taking submissions into account.

Clinvar: 2024-03-31

Clinvar\_SV: 2023-01-19

ClinGen Regions: 30\_Jan\_2023

GnomAD STR: 2022-04-24

MITOMAP Known Variants: 2021-05-26

dbSNP: 155


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