LogoLogo
Illumina KnowledgeIllumina SupportSign In
  • Home
  • Overview
    • Welcome
    • What's New
      • Cloud Software Update
      • Local Software Update
  • Configure
    • Configuration
      • Custom Case Data
      • Pipeline and QC Configuration
      • Preferred Transcripts
      • Custom Annotations
      • Disease Configuration
      • Variant Filters
      • Variant Flag Groups
      • Actionability Classifications
      • Report Templates
        • Customizations
      • Report Automation
      • Test Definitions
      • Data Upload
        • Data Upload from User Storage (Connected Insights - Cloud and Connected Insights - Local)
        • Data Upload from ICA or BSSH (Connected Insights - Cloud)
        • Supported Pipelines
          • DRAGEN TruSight Oncology 500 Analysis Software v2.6.0 (with HRD)
          • DRAGEN TruSight Oncology 500 Analysis Software v2.6.0
          • DRAGEN TruSight Oncology 500 Analysis Software v2.5.3 (with HRD)
          • DRAGEN TruSight Oncology 500 Analysis Software v2.5.3
          • DRAGEN TruSight Oncology 500 Analysis Software v2.5.2 (with HRD)
          • DRAGEN TruSight Oncology 500 Analysis Software v2.5.2
          • DRAGEN TruSight Oncology 500 Analysis Software v2.1.1 (with HRD)
          • DRAGEN TruSight Oncology 500 Analysis Software v2.1.1
          • DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.1
          • DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.6.0
          • DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.5.0
          • DRAGEN TruSight Oncology 500 ctDNA Analysis Software v2.1.1
          • DRAGEN Amplicon v4.3
          • DRAGEN Amplicon v4.2
          • DRAGEN Amplicon v4.1
          • DRAGEN RNA v4.3
          • DRAGEN RNA v4.2
          • DRAGEN RNA v4.1
          • DRAGEN Enrichment v4.3
          • DRAGEN Enrichment v4.2
          • DRAGEN Enrichment v4.1
          • DRAGEN for Illumina cfDNA Prep with Enrichment v4.0.3
          • DRAGEN Somatic Whole Genome v4.3
          • DRAGEN Somatic Whole Genome v4.2
          • DRAGEN Somatic Whole Genome v4.1
          • TruSight Tumor 170 Local App v2.0.1
          • Local Run Manager TruSight Tumor 15 Analysis Module v2.1
        • Custom Pipeline Configuration
          • VCF Input Requirement
          • TMB, MSI, GIS Input Requirement
        • Custom Case Data Upload
    • Upload Assertions
    • Local Installation Guide
      • Overview
      • Prerequisites
      • Download Connected Insights Package
      • Install Connected Insights Software
      • Install License File
      • Sign In to Connected Insights
      • Installation Status Messages
      • Local Configurations
      • Administration Console (Connected Insights - Local)
      • Configure External Storage (Connected Insights - Local)
  • Manage cases
    • Cases Page
    • Cases List
      • Case Metadata Upload
  • Interpret and report
    • Case Page
    • Case Details
      • Merge Cases
    • Overview Tab
      • Classification & Risk Stratification Prediction
    • Visualize Tab
    • Variants Tab
      • Modify Columns
      • Apply Variant Filters
        • Filter by Variant Category
        • Variant Details Filters
        • Variant Quality Filters
        • Functional Impact Filters
        • Disease Association Filters
        • Variant Frequency Filters
        • Flags Filter
        • Filtering Logic
      • IGV Visualizations
    • Lab QC Tab
    • Report Tab
    • View Biomarker Details
      • Biological Classification
      • Actionability
      • Clinical Trials
      • Oncogenicity Prediction
      • Visualize
      • Variant Overview
      • Gene Overview
      • Cancer Datasets
      • Computer Predictors
      • Population
    • Interpret a Biomarker
      • Create Clinical Trials
      • Create Gene Descriptions
      • Manage Assertions
    • Variant Transcripts
    • Add Variant
  • Resources and References
    • Glossary
    • APIs
      • Ingest Cloud Analysis Data API (Connected Insights - Cloud Only)
      • Case APIs
      • Report APIs
      • Audit Log APIs
    • Troubleshooting
      • Overview
      • Audit Log
      • Data Backup (Connected Insights - Local)
      • Software Errors and Corrective Actions
      • How To
      • Technical Assistance
    • Pricing and Usage
    • Security and Compliance
    • Release Notes
Powered by GitBook
On this page
  • Add and Configure a Variant Filter
  • Edit a Variant Filter
  • Duplicate a Variant Filter
  • Archive a Variant Filter
  • Default Filters

Was this helpful?

Export as PDF
  1. Configure
  2. Configuration

Variant Filters

The Variant Filters section describes how to add, configure, duplicate, or archive variant filters.

Add and Configure a Variant Filter

  1. On the top toolbar, select Configuration.

  2. Select the Test Components tab.

  3. Navigate to Variant Filters and select New.

  4. Navigate to the Condition Group section and enter the applicable genes in the Genes field.

  5. [Optional] Select the Include genes from diseases check box.

  6. Select Apply.

  7. Select Include or Exclude from the drop-down list for each gene.

  8. For Variant Category, select the field to open up a drop-down list of variants that can be included or excluded.

  9. Select the check boxes next to the applicable variant types.

  10. Select Add Criteria and select the applicable criteria from the drop-down list (for example, Cancer Hotspot Samples).

  11. Select Include or Exclude from the drop-down list for the criteria.

  12. To include or exclude additional criteria, repeat steps 10 and 11.

  13. For AND or OR, select Add Condition Group to add any other applicable condition groups.

  14. [Optional] Select Reset to undo the changes to the condition groups.

  15. Select Save.

Edit a Variant Filter

  1. On the top toolbar, select Configuration.

  2. Select the Test Components tab.

  3. For Variant Filters, select a filter.

  4. Select Edit.

  5. Select Save.

Duplicate a Variant Filter

  1. On the top toolbar, select Configuration.

  2. Select the Test Components tab.

  3. For Variant Filters, select the applicable filter.

  4. In the right-hand pane, select Duplicate.

  5. Select Save.

Archive a Variant Filter

  1. On the top toolbar, select Configuration.

  2. Select the Test Components tab.

  3. For Variant Filters, select the applicable filter.

  4. In the right-hand pane, select Archive.

  5. To confirm, select Yes, change.

Default Filters

Connected Insights provides the following default filters to assist in preliminary test implementation:

Filter

Description

Pre-configured Demo Filter

Filters for rare coding small variants, copy number variants, unidirectional gene-fusions, and splice variants.

Pre-configured Small Variant Demo Filter

Filters for rare coding small variants.

Pre-configured CNV Demo Filter

Filters for CNVs.

Pre-configured Focal CNV Demo Filter

Filters for CNVs that exhibit a focal (>=7 CN, >3.5 FC, <2 CN, or <=0.5 FC) copy number change.

Pre-configured SV Demo Filter

Filters for unidirectional gene-fusions called via DNA data.

Pre-configured RNA Demo Filter

Filters for RNA splice variants and unidirectional gene-fusions.

Pre-configured TSO 500 RNA Demo Filter

Filters for RNA splice variants in AR / MET / EGFR and undirectional gene-fusions.

Pre-configured OVS1 + OP4 Demo Filter

Filters for rare gene disrupting small variants or splice variants in a known tumor suppressor gene.

Pre-configured AML Demo Filter

Filters for rare coding small variants, unidirectional gene-fusions, splice variants, and large ( >= 5 Mbp) structural / copy number variants in genes known to be involved in AML.

PreviousDisease ConfigurationNextVariant Flag Groups

Last updated 4 months ago

Was this helpful?

The Genomic Region criteria is not available when creating a filter from configuration but can be included when adding/editing filters in Variant grid . For more information, refer to .

Update the applicable settings. For more information, refer to .

[Optional] Adjust the condition group settings. For more information, refer to .

Add and Configure a Variant Filter
Add and Configure a Variant Filter
Add and Configure a Variant Filter