# Cancer Datasets

This section provides details on the variant’s presence in different datasets.

## Lab Frequency

Displays the number of samples with the variant in the given workgroup presented per disease. To be accounted for, the variant:

* Need to be present in any uploaded VCF or variant file
* Need to have a flag PASS in the VCF variant filters
* Doesn’t need to be interpreted or included in the report
* Can have any variant origin (predicted germline or suspected somatic)

❗ Cases processed prior to version 4.0 of Connected Insights will not appear in the lab frequency.

## Cancer Hotspots

The section displays:

* Number of samples in the [Cancer Hotspots database](https://www.cancerhotspots.org) with the variant for the selected transcript
* Highest number of samples in the [Cancer Hotspots database](https://www.cancerhotspots.org) for the variant across transcripts

## COSMIC

The section displays:

* Genomic Mutation ID in the COSMIC database
* Number of samples with the variant in the COSMIC database displayed per cancer site, for example, breast
* Number of samples with the variant in the COSMIC database displayed per histology, for example, carcinoma