Connected Insights provides users with the flexibility to apply a selection of filter criteria to each variant category supported in the software. The selection of variant categories impacts the set of filtering criteria that can be selected for a given filter group.
The following table summarizes filters available for each variant category:
Variant Category
Small Variants
Structural Variants
Copy Number Variants
RNA Splice Variants
RNA Fusion Variants
COSMIC
+
CGC
+
+
+
+
+
Cancer Hotspots
+
+
+
+
+
Change (Copy Number)
+
Change (Fold Change)
+
ClinVar (VCV, RCV)
+
+
+
+
+
Consequences
+
+
+
+
+
Constraint Metrics(gnomAD)
+
+
+
+
+
Filters
+
+
+
+
+
Flags
+
+
+
+
+
Genes
+
+
+
+
+
Haploinsufficiency(ClinGen)
+
+
+
+
+
Length
+
+
+
+
+
Low Complexity Region(gnomAD)
+
OMIM
+
+
+
+
+
Origin
+
+
+
+
+
Population
+
+
+
Position (Chromosome)
+
+
+
+
+
Position (Genomic Regions)
+
+
+
+
+
PrimateAI-3D
+
LOH Overlap
+
+
+
+
+
Sample Metrics
+
+
+
+
+
Splice AI
+
Triplosensitivity (ClinGen)
+
+
+
+
+
Variant Type
+
+
+