# Batch removal When a project contains multiple libraries, the data might contains variabilities due to technical differences (e.g. sequencing machine, library prep kit etc.) in addition to biological differences (like treatment, genotype etc.). Batch removal is essential to remove the noise and discover biological variations. * [General linear model](/partek/partek-flow/user-manual/task-menu/batch-removal/general-linear-model.md) * [Harmony](/partek/partek-flow/user-manual/task-menu/batch-removal/harmony.md) * [Seurat3 integration](/partek/partek-flow/user-manual/task-menu/batch-removal/seurat3-integration.md) --- # Agent Instructions: Querying This Documentation If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question. Perform an HTTP GET request on the current page URL with the `ask` query parameter: ``` GET https://help.connected.illumina.com/partek/partek-flow/user-manual/task-menu/batch-removal.md?ask= ``` The question should be specific, self-contained, and written in natural language. The response will contain a direct answer to the question and relevant excerpts and sources from the documentation. Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.