> For the complete documentation index, see [llms.txt](https://help.connected.illumina.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.connected.illumina.com/partek/partek-flow/user-manual/task-menu/batch-removal.md).

# Batch removal

When a project contains multiple libraries, the data might contains variabilities due to technical differences (e.g. sequencing machine, library prep kit etc.) in addition to biological differences (like treatment, genotype etc.). Batch removal is essential to remove the noise and discover biological variations.

* [General linear model](/partek/partek-flow/user-manual/task-menu/batch-removal/general-linear-model.md)
* [Harmony](/partek/partek-flow/user-manual/task-menu/batch-removal/harmony.md)
* [Seurat3 integration](/partek/partek-flow/user-manual/task-menu/batch-removal/seurat3-integration.md)


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