Common Product Features

Run Planning

Application	Supported in BSSH Run Planner	Note
Heme WGS TO	Yes	Mixed flow cell, auto-launch
Solid WGS TN	No	Only Header and TN_Data sections required in SampleSheet.csv

Sample Sheets

All the clinical research workflow pipelines support only v2 sample sheet and requires index2 to be in forward orientation, with bcl-convert SoftwareVersion >= 4.4. The pipelines are stil compatible with legacy sample sheets where the BCLConvert_Settings section has SoftwareVersion < 4.4. Sample sheet v1 is no longer supported.

ICA Cloud Applications

The clinical research workflow pipelines in the ICA cloud support post-processing scripts to be executed after the completion of the pipeline analysis.

ICI Variant Interpretation

The clinical research workflow pipelines support automatic data ingestion or manual upload into ICI for variant interpretation after the analysis is completed in ICA, or using a DRAGEN on-premises server locally.