Getting Started
Illumina Connected Multiomics is a cloud-based software platform designed for biologists to perform tertiary analysis of multiomics data for research purposes. It enables users to organize and manage biological data into studies, apply statistical methods, reference knowledge sources for biological interpretation, correlate results across various omics data types and modalities, and deliver visualization tools to support result interpretation. This functionality streamlines the process from samples to multiomics insights, accelerating data interpretation and publication efforts.
Set Up Connected Multiomics
To register your software, refer to the Software Setup documentation.
During the software registration process, you will need to create a domain and workgroup. Domains and Workgroups are used by Illumina Software to control access to different customer’s data and assets. When logging into Connected Multiomics, you will be required to select a domain and workgroup to establish the context for your work.
Make sure all users are added to the workgroup and that the workgroup has the necessary permissions to access the Connected Multiomics application. For more information, refer to the Workgroup documentation.
Log In To Connected Multiomics
Once you have successfully set up your account and created your domain and workgroup, you can log in to ICM. Follow the steps below.
Access the software by clicking domain URL link provided in the confirmation email.
Adding the URL link to your browser bookmark is recommended for easy access in the future.
Log into your domain by entering your credentials into the login screen, then click Sign In.
Once sign in, you will be directed to Product Dashboard page. Select the Illumina Connected Multiomics application tile from your Product Dashboard.
Select your workgroup from the dropdown menu.
Once you select a workgroup, it will automatically be chosen during future logins. This selected workgroup will not be applied to other Illumina Connected Software applications. If you have only one workgroup, it will be selected for you by default.
You will now be directed to the Studies overview screen. In the top right, you can click on your profile button to see your current workgroup, domain, and subscription information. To change workgroups, you can click on "Switch workgroup" and select your desired workgroup from the dropdown menu.
Explore Onboarding Resources
When you log into Connected Multiomics for the first time, you will be greeted with a Welcome Screen.
Click Get started to take you directly to the home page of the application and begin navigating on your own.
To explore a read-only interactive environment with pre-assembled studies, analyses, results, and visualizations, choose Try with demo data to bring you to the Connected Multiomics Tutorial Study. The source demo files used in the Tutorial Study are available to add to and use in your own Studies later, too.
Select Help resources for easy links to user guide content, including a helpful query box, detailed walkthrough tutorials, instructional videos, and software release notes.
You may return to the Welcome Screen and these selections anytime you'd like by selecting the 
icon on the top right of the application window next to your profile.
Navigate Connected Multiomics
In the Connected Multiomocs navigation on the left panel, you'll see the following structure:
Studies are your primary work locations which contain your data and tools to execute your analyses. Studies can be considered as a binder for your work and information.
Analyses are a list of the analyses you have launched. Here, you can access graphs, view visualizations, and gather insights related to your data.
Sample Groups are collections of samples that are organized based on one or more metadata fields, allowing you to group and manage data effectively for analysis.
Click on each section below to learn more.
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