Software Release Notes

This page contains the release notes for the current release. See the subpages for historic release notes.

On December 20, 2025, AWS will be retiring the F1 instances, referred to in this guide as FPGA. By November 1st, 2025 support of F1 (FPGA) instances will be decommissioned in ICA to ensure timely switchover. New versions of existing DRAGEN workflows have been created to support F2 (FPGA2) instances. Please consult the DRAGEN BSSH/ICA end of life roadmap for more information on switching over.

Please migrate to F2 for improved capacity and performance with up to 40% reduced turnaround time for analysis.

2025 Sep 24 - ICA v2.39.0

New Features and Enhancements

• General

  • The reference data screens have been upgraded to be in line with the standard look and feel.

  • The Base query screens have been upgraded to be in line with the standard look and feel, and for easier navigation.

  • A column name called Source has been added to the Docker images view. This also to differentiate between internal and external Docker images. By default, this column Is hidden and can be added with the column selector (top right).-

• Data Management

  • -

• Bench

  • You can now choose clusters in addition to single nodes for your workspaces for better performance with Bench Images that support this feature. You can have a dedicated cluster and for the cluster members, you can choose to use a static number of nodes or dynamic scaling.

  • FPGA2 instances are now also available in workspaces.

  • DRAGEN is now available to all users in Bench.

  • Users can now edit running workspaces to update the shutdown timer, shutdown reminder and auto restart reminder.

• Flow

  • New bench images are provided for Spark, SunGrid Engine and clusters.

  • ICA will display a message in the analysis status field when the system's underlying cloud provider is at low capacity for storage resources

  • A limit of 100 report configurations per API pipeline creation call has been introduced.

• Cohorts * Promoter AI scores are now integrated into the Cohort Analysis Module, providing additional insights in the variants table alongside existing scores like PrimateAI and SpliceAI.

  • Updated data ingestion rules so that the sex/gender attribute is now optional for all nonCNV data types, simplifying metadata requirements and reducing ingestion errors.

Fixed Issues

• General

  • Performance improvements for event logging

  • When attempting to accept an ICA Project invite via public domain, an error message is displayed to indicate that this is not allowed. You have to be logged in via a private domain in order to be able to accept the invite.

  • Fixed an issue where job status change events would be received twice for SNS/SQS subscriptions

• Base

  • -

• Bench

  • Corrected input validation for storage size during workspace configuration.

• Data Management

  • -

• Flow

  • Improved input form validations for Pipelines.

  • Improved pipeline development in Bench when importing a flow pipeline.-

• Cohorts

  • The system now provides clear error messages in JSON format—rather than confusing HTML—when project link notifications fail, making it easier to understand and troubleshoot issues.

  • Fixed an issue in the Correlation tab where the scatter plot failed to update when switching between cohorts after applying filters.

  • Corrected the axis titles in RNA expression scatter plots within the Correlation tab to ensure accurate mathematical representation of log-transformed expression ratios.

  • Fixed an issue where gene lists in Gene Expression, Somatic Mutation, and Copy Number Variation tabs failed to sort correctly by gene name, improving data navigation in cohort comparisons.

  • Resolved an issue where legend colours in gene expression, somatic mutation, and copy number variation charts did not match across cohort comparison views, ensuring consistent and accurate visual interpretation