Custom Panel

Abbreviation	Definition
NGS	next-generation sequencing
pangolin	phylogenetic assignment of named global outbreak lineages

Category	Test information
RUO	For Research Use Only. Not for use in diagnostic procedures.
URL	See https://www.illumina.com/ for additional information.
Pango lineage	The most likely Pango (phylogenetic assignment of named global outbreak) lineage is assigned to the majority consensus SARS-CoV-2 genome sequence using pangolin 4.3.1 (Áine O'Toole & Emily Scher et al. 2021 Virus Evolution DOI:10.1093/ve/veab064).
Limitations	Custom panel data analysis using DRAGEN Microbial Enrichment Plus aligns human-dehosted next-generation sequencing (NGS) reads to reference sequences. Contamination with microorganisms is possible during specimen collection, transport, and processing. Reads from closely related microorganisms may align to reference sequences based on sequence homology. Alignment of reads to a microorganism does not confirm that the microorganism is causing symptoms, is viable, or is infectious. Results should be interpreted in the context of all available information. Other sources of data may be required for confirmation.