Software Updates (Connected Insights - Local)

The Software Update page allows you to manage updating or initial installation of Connected Insights - Local software and the dependent packages. It provides details into the currently installed versions of software packages. Additionally, this page manages license updates, providing details on the last installed license date and the current remaining Genome Equivalent Sample (GEs) balance.

The following packages are supported:

• Connected Insights - Local software: Updates only

• Illumina Connected Annotations: Updates or initial installation

• Illumina Connected Insight Data Reference: Updates or initial installation

• Knowledge base files: Updates or initial installation

• License file: Updates only

For the initial installation of Connected Insights - Local software and the license file, see Install Connected Insights - Local software and Install License File, respectively.

Install or Update software and dependent package

To install or update software or its dependent packages, refer to the instructions below:

1. From any page, click your username in the top right, select Administration Console, then Software Update. The Administration Console page is only accessible by Connected Insights - Local software users with an Administration role.

2. On the right-side pane, choose one of the options below based on where the packages are available:

   • DRAGEN server v4 path /staging/icipackages/

   • Mounted external storage drive (e.g. NAS) located at /mnt/<ici_mount>/icipackages/

   • USB device connected and mounted to the DRAGEN server v4 (e.g., located in /media/usbinstall/)

   • Local computer (only for Knowledge Base files and the license file). For this method, proceed to subsections Update Knowledge Base from Local Computer and Update License from Local Computer below.

   ❗ Before starting installation or updates, ensure only Connected Insights - Local software package(s) are available in one of the supported package locations specified above.

3. Click Check for Updates.

4. The application displays the compatible Connected Insights - Local software package(s) with an Install Now button next to each. Additionally, there is an Install All button which installs or updates all the dependent packages available within the selected location.

   The Install All option is not provided when a higher version of Connected Insights - Local software package is available under the selected package location. In such cases, the Connected Insights - Local software must be installed followed by the dependent packages.

5. Select Install Now or Install All based on the options provided.

6. A confirmation pop-up will appear displaying the approximate time for installing or updating the selected package(s) and states the application will be inaccessible during this time.

7. Click Install Now in the confirmation pop-up.

   ❗ The application checks for the conditions below and only proceeds when the validations are successful. If one or multiple are not met, a pop-up window appears indicating the error and installation/updating will be blocked. Select Close, fix the conditions below, and try again.

   • Package files integrity checks pass.

   • No Case processing is in progress.

   • /staging (on the DRAGEN server v4) has minimum of 200 GB free space.

If the validations above succeed, application starts the install or update process and displays the progress of package install/updates. During the install or update process, the application is inaccessible. After the install or update is completed, the screen refreshes to the Connected Insights - Local software login screen with a success message. Install or update any remaining packages if not done already.

• Then, if not done already (mainly applies to first-time installation), follow the instructions in Configuration to further set up Connected Insights - Local software and Data Upload from User Storage (Connected Insights - Cloud and Connected Insights - Local) to ingest cases from secondary analysis output data.

If an update for an existing package fails, the application will automatically try to revert to the previous version of the package. You can then attempt to reinstall or re-upload the package from the Software Update page. If the rollback process also fails, the application will display an "Update Failed" message and restrict access to the application. For further troubleshooting contact Illumina Support.

Update Knowledge Base from Local Computer

The application allows you to install or update Knowledge Base files by uploading the files directly from user's personal computer. Refer to the instructions below:

1. From any page, click your username in the top right, select Administration Console, then Software Update. The Administration Console page is only accessible by Connected Insights - Local software users with an Administration role.

2. On the right-side pane, select the Local computer (only for Knowledge Base and license file) option.

3. Select the Knowledge Base file from your personal computer.

4. After the upload is complete, select Install.

5. A confirmation pop-up will appear displaying the approximate time for installing or updating the selected Knowledge Base package and states the application will be inaccessible during this time.

6. Click Install Now in the confirmation pop-up window.

❗ The application checks for the conditions below and only proceeds when the validations are successful. If one or multiple are not met, a pop-up window appears indicating the error and installation/updating will be blocked. Select Close, fix the conditions below, and try again.

• Package files integrity checks pass.

• No Case processing is in progress.

• /staging (on DRAGEN server v4) has minimum of 200 GB free space.

If the validations above succeed, the application starts the install or update process and displays the progress. During the install or update process, the application is inaccessible. After the install or update is completed, the screen refreshes to the Connected Insights - Local software login screen with a success message.

Update License (ConnectedInsights-QuotaLicense.bin) from Local Computer

The application allows you to update Genome Equivalent Sample (GEs) balance by uploading the ConnectedInsights-local-QuotaLicense.bin file directly from user's personal computer. Download the license files sent by the Illumina Sales/Customer Support team on your personal computer and select ConnectedInsights-local-QuotaLicense.bin for this step. Refer to the instructions below:

1. From any page, click your username in the top right, select Administration Console, then Software Update. The Administration Console page is only accessible by Connected Insights - Local software users with an Administration role.

2. On the right-side pane, select the Local computer (only for Knowledge Base and license file) option.

3. Select the ConnectedInsights-local-QuotaLicense.bin license file.

4. After the upload is complete, select Install.

❗ The application checks for the conditions below when updating a license file and only proceeds when the validations are successful. If one or multiple are not met, a pop-up window appears indicating that the update cannot be installed. Select Close, fix the conditions below and try again.

• The package file integrity checks pass.

• The license file is intended for the target DRAGEN server v4.

If the above validation succeeds, the application proceeds to update the license and a success message is displayed. Upon successful License update, the amount of remaining GEs is refreshed to the current aggregated value under the License File section of the Software Update page.