View Variant Details

The Biomarker Details page brings together key information and actions related to variants. The page exists for individual variants and genome-wide biomarkers like TMB and MSI. You can use the Biomarker Details page to do the following:

• Interpret the variant and include it in the report.

• Review assertions already created for the variant. For more information, refer to Biological Classification Assertions.

• Review sign-off reports that included the variant. For more information, refer to Biological Classification Assertions.

• Review variant information related to oncology: – Knowledge bases. For more information, refer to Actionability. – Clinical trials. For more information, refer to Clinical Trials.

• Review variant information. For more information, refer to Variant Overview. – Annotation details – Gene information – Records in external sources – Functional impact predictions – Population frequency

• Set gene transcripts. For more information, refer to Transcripts.

To open the Biomarker Details page, select Interpret for a specific variant in the Overview or Variants tab.