# Multi-selection of variants and bulk actions

By using the multi-selection mode, you can speed up review by applying actions to multiple variants at once. This makes it easier to apply tags, assign pathogenicity, and review status without handling each variant individually.

{% hint style="info" %}
**Note:** Multi-selection and bulk actions are only available in non-finalized cases to maintain data integrity.
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### Multi-selection of variants

1. Hover over a variant to reveal a checkbox at the start of the line;
2. Selecting a checkbox activates the **Multi-select actions bar**, replacing the Search bar.
3. Checkboxes appear for all variants in the current view.
4. Select variants individually or use the **Select all** checkbox.

   **Important:** Select all applies only to variants currently displayed on the page, not all variants matching your filters.

![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-adffcde7eb1cae43e6b94aa87e2224258f4dc10f%2FREADME_1_multi%2Bselect.gif?alt=media)

## Bulk actions:

### 1. View/ Un-view variants

Change the review status for multiple variants at once:

1. Select the variants of interest.
2. In the Multi-select actions bar, click the **Viewed** icon.
3. Choose **Viewed** or **Un-viewed**.

{% hint style="info" %}
**Note:** Variants already tagged by a user cannot be marked as *Un-viewed*.
{% endhint %}

![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-39ecb6d7cff7ea3c8476daa305f7631086d3575b%2Fmultiselection_of_variants_and_bulk_actions_340%2B_2.png?alt=media)

### 2. Assign/ Remove tags

Assign or manage tags across multiple variants at once:

**Assign tags**

1. Select the variants of interest.
2. Click the **Tag** icon in the Multi-select actions bar.
3. Choose a tag from the dropdown menu.
   1. If a tag is already assign to at least one variant within the selected variants of interest, a confirmation window will appear showing the current assigned tag and the new tag per variants.
   2. When multiple tags per variant are enabled, tags are always **added in addition to existing tags.** no confirmation window will appear.
   3. All tags assigned to a variant are displayed in the Tag column.
   4. If both user tags and AI tags exist, only **user tags** appear in the column.

![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-02228b790106810ab9a88a9aec321590fe357a9f%2Fmultiselection_of_variants_and_bulk_actions_340%2B_3.png?alt=media)

**Remove tags**

1. Select the variants of interest.
2. Click the **Tag** icon.
3. Choose one of the following:

   1. **Clear** – removes user-assigned tags.
   2. **Not relevant** – removes tags assigned by Emedgene.

   ![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-3e6b5cfdfb1347b4300f10fa92b45da75187ddef%2Fmultiselection_of_variants_and_bulk_actions_340%2B_6_image.png?alt=media)

### 3. Assign/ Clear pathogenicity

Set or remove pathogenicity classifications for multiple variants:

**Assign pathogenicity**

1. Select the variants of interest.
2. In the Multi-select actions bar, click the **Pathogenicity** icon.
3. Choose a classification (Pathogenic, Likely Pathogenic, VUS, Likely Benign, Benign).

{% hint style="info" %}
**Note:** Only tagged variants can have pathogenicity assigned.
{% endhint %}

![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-0782107f0ba1ddd13263225eb282d1496b188dfc%2Fmultiselection_of_variants_and_bulk_actions_340%2B_4.png?alt=media)

**Clear pathogenicity**

1. Select the variants of interest.
2. In the Multi-select actions bar, click the **Pathogenicity** icon.
3. Select **Clear** to remove the existing classification.

![](https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-b8612cbc91b56a7662211ff6485d76a393f58f68%2Fmultiselection_of_variants_and_bulk_actions_340%2B_5.png?alt=media)

{% hint style="success" %}
**Tips:**

* Use **bulk tagging** to ensure consistency across variants that share biological or interpretive context.
* Combine **tags and pathogenicity assignments** in bulk to streamline reporting prep.
* For large variant sets, apply filters first to narrow down your view before using multi-selection.
  {% endhint %}

{% hint style="danger" %}
**Warnings:**

* Bulk edits apply **immediately** to all selected variants. Double-check your selections before applying.
* Removing tags or pathogenicity affects all team members working on the case—coordinate with your team to avoid conflicts.
* Once a case is finalized, bulk actions are disabled to protect case integrity.
  {% endhint %}