# Organization DB management

Use the **Organization DB Management** card to manage [**organization databases**](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/settings/organization_settings_-330+/workbench-and-pipeline/organization-db-management/organization-databases)—custom variant datasets that [support variant interpretation](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/tertiary-analysis-pipeline/annotations-from-organization-databases). Here you can:

* **Review database details** in a table:
  * **Database name** and **type**, **file**, **genome reference**, **variant type**, **date last edited**
  * **Active** (On/Off): Indicates whether annotation from the database is applied to variants in new and reanalyzed cases
  * **AI Shortlist** (On/Off): Indicates whether the AI Shortlist factors in allele frequencies from the database. When enabled, variants with an allele frequency above 10% are excluded from the list
  * For CNV databases: **Candidate (C) and annotation (A)** [**overlap percentages**](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/variant_page/related_cases_section/cnv_overlap_percentage) used for comparing CNV variants in cases vs. the database
* **Search:** Use the search bar above the table to look up a database by its name
* **Download**: Click the <i class="fa-arrow-down-from-line">:arrow-down-from-line:</i> Download icon on the right to export a database as a VCF file
* [**Configure**](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/settings/organization_settings_-330+/workbench-and-pipeline/organization-db-management/configuring-an-organization-database) databases (requires special [permissions](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/settings/user_roles/iam-scopes-emedgene-roles))
* [**Modify**](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/settings/organization_settings_-330+/workbench-and-pipeline/organization-db-management/configuring-an-organization-database/modifying-database-settings) database settings (requires special [permissions](https://help.connected.illumina.com/emedgene/emedgene-analyze-manual/settings/user_roles/iam-scopes-emedgene-roles))

<figure><img src="https://1131024994-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FGCW0DnLlE7QjoZPNmKIi%2Fuploads%2Fgit-blob-32aa330f801564465e516c6eab39c0804dd842d2%2Fimage%20(48).png?alt=media" alt=""><figcaption><p>Figure 1. Organization DB management card</p></figcaption></figure>