Organization DB management

Use the Organization DB Management card to manage organization databases—custom variant datasets that support variant interpretation. Here you can:

• Review database details in a table:

  • Database name and type, file, genome reference, variant type, date last edited

  • Active (On/Off): Indicates whether annotation from the database is applied to variants in new and reanalyzed cases

  • AI Shortlist (On/Off): Indicates whether the AI Shortlist factors in allele frequencies from the database. When enabled, variants with an allele frequency above 10% are excluded from the list

  • For CNV databases: Candidate (C) and annotation (A) overlap percentages used for comparing CNV variants in cases vs. the database

• Search: Use the search bar above the table to look up a database by its name

• Download: Click the Download icon on the right to export a database as a VCF file

• Configure databases (requires special permissions)

• Modify database settings (requires special permissions)

Figure 1. Organization DB management card