Prerequisites for accessing the DRAGEN QC report

NGS case

Option 1: FASTQ case

1

Run a FASTQ case in Emedgene.

2

Since DRAGEN analysis is integrated into Emedgene secondary analysis pipeline, QC reports are automatically generated in the system.

Option 2: VCF case—Bring your own DRAGEN (BYOD)

1

Run DRAGEN analysis externally.

2

Prepare a TAR archive containing DRAGEN QC metrics files.

3

Upload the TAR archive and the sample VCF file to Emedgene.

This workflow is supported for batch case upload via UI and CLI and API-based case creation.

Array case

Array cases start from VCF input files. DRAGEN QC for array cases is supported on Emedgene v100.39.0 and later.

VCF case—Bring your own DRAGEN (BYOD)

1

Run DRAGEN analysis externally using DRAGEN Array v1.3.0.

2

Upload the .annotated_cyto.json DRAGEN QC metrics file, the sample VCF file, and the .gt_sample_summary.json file to Emedgene.

This workflow is supported for batch case upload via UI and CLI and API-based case creation.